Harnessing hematopoietic stem cell low intracellular calcium improves their maintenance in vitro

The specific cellular physiology of hematopoietic stem cells (HSCs) is underexplored and their maintenance in vitro remains challenging. We discovered that culture of HSC in low calcium increased their maintenance as determined by phenotype, function and single cell expression signature. HSCs are en...

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Publicado en:Cell Stem Cell
Main Authors: Luchsinger, Larry L, Strikoudis, Alexandros, Danzl, Nichole M, Bush, Erin C, Finlayson, Michael O, Satwani, Prakesh, Sykes, Megan, Yazawa, Masayuki, Snoeck, Hans-Willem
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7649753/
https://ncbi.nlm.nih.gov/pubmed/31178255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.05.002
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