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Targeting Glutaminolysis: New Perspectives to Understand Cancer Development and Novel Strategies for Potential Target Therapies

Metabolism rewiring is an important hallmark of cancers. Being one of the most abundant free amino acids in the human blood, glutamine supports bioenergetics and biosynthesis, tumor growth, and the production of antioxidants through glutaminolysis in cancers. In glutamine dependent cancer cells, mor...

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發表在:Front Oncol
Main Authors: Wang, Zhefang, Liu, Fanyu, Fan, Ningbo, Zhou, Chenghui, Li, Dai, Macvicar, Thomas, Dong, Qiongzhu, Bruns, Christiane J., Zhao, Yue
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7649373/
https://ncbi.nlm.nih.gov/pubmed/33194749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.589508
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