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Targeting Glutaminolysis: New Perspectives to Understand Cancer Development and Novel Strategies for Potential Target Therapies

Metabolism rewiring is an important hallmark of cancers. Being one of the most abundant free amino acids in the human blood, glutamine supports bioenergetics and biosynthesis, tumor growth, and the production of antioxidants through glutaminolysis in cancers. In glutamine dependent cancer cells, mor...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Wang, Zhefang, Liu, Fanyu, Fan, Ningbo, Zhou, Chenghui, Li, Dai, Macvicar, Thomas, Dong, Qiongzhu, Bruns, Christiane J., Zhao, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7649373/
https://ncbi.nlm.nih.gov/pubmed/33194749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.589508
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