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The Impact of OnabotulinumtoxinA vs. Placebo on Efficacy Outcomes in Headache Day Responder and Nonresponder Patients with Chronic Migraine

INTRODUCTION: The phase 3 PREEMPT trials demonstrated efficacy and tolerability of onabotulinumtoxinA for headache prevention in adults with chronic migraine. OnabotulinumtoxinA significantly reduced headache frequency from baseline vs. placebo at 24 weeks; however, this measure may not fully captur...

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Dettagli Bibliografici
Pubblicato in:Pain Ther
Autori principali: Silberstein, Stephen D., Diener, Hans-Christoph, Dodick, David W., Manack Adams, Aubrey, DeGryse, Ronald E., Lipton, Richard B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Healthcare 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648816/
https://ncbi.nlm.nih.gov/pubmed/33026630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40122-020-00199-9
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