Alzheimer‐related altered white matter microstructural integrity in Down syndrome: A model for sporadic AD?

INTRODUCTION: Virtually all adults with Down syndrome (DS) develop Alzheimer's disease (AD)‐associated neuropathology by the age of 40, with risk for dementia increasing from the early 50s. White matter (WM) pathology has been reported in sporadic AD, including early demyelination, microglial a...

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Vydáno v:Alzheimers Dement (Amst)
Hlavní autoři: Rosas, H. Diana, Hsu, Eugene, Mercaldo, Nathaniel D., Lai, Florence, Pulsifer, Margaret, Keator, David, Brickman, Adam M., Price, Julie, Yassa, Michael, Hom, Christy, Krinsky‐McHale, Sharon J., Silverman, Wayne, Lott, Ira, Schupf, Nicole
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648416/
https://ncbi.nlm.nih.gov/pubmed/33204811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12040
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