Next-generation GRAB sensors for monitoring dopaminergic activity in vivo

Dopamine (DA) plays a critical role in the brain, and the ability to directly measure dopaminergic activity is essential for understanding its physiological functions. We therefore developed red fluorescent GPCR-activation–based DA (GRAB(DA)) sensors and optimized versions of green fluorescent GRAB(...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Sun, Fangmiao, Zhou, Jingheng, Dai, Bing, Qian, Tongrui, Zeng, Jianzhi, Li, Xuelin, Zhuo, Yizhou, Zhang, Yajun, Wang, Yipan, Qian, Cheng, Tan, Ke, Feng, Jiesi, Dong, Hui, Lin, Dayu, Cui, Guohong, Li, Yulong
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648260/
https://ncbi.nlm.nih.gov/pubmed/33087905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-00981-9
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