Single-Cell Profiling Reveals Divergent, Globally Patterned Immune Responses in Murine Skin Inflammation

Inflammatory response heterogeneity has impeded high-resolution dissection of diverse immune cell populations during activation. We characterize mouse cutaneous immune cells by single-cell RNA sequencing, after inducing inflammation using imiquimod and oxazolone dermatitis models. We identify 13 CD4...

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Publicado en:iScience
Autores principales: Liu, Yale, Cook, Christopher, Sedgewick, Andrew J., Zhang, Shuyi, Fassett, Marlys S., Ricardo-Gonzalez, Roberto R., Harirchian, Paymann, Kashem, Sakeen W., Hanakawa, Sho, Leistico, Jacob R., North, Jeffrey P., Taylor, Mark A., Zhang, Wei, Man, Mao-Qiang, Charruyer, Alexandra, Beliakova-Bethell, Nadejda, Benz, Stephen C., Ghadially, Ruby, Mauro, Theodora M., Kaplan, Daniel H., Kabashima, Kenji, Choi, Jaehyuk, Song, Jun S., Cho, Raymond J., Cheng, Jeffrey B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648132/
https://ncbi.nlm.nih.gov/pubmed/33205009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101582
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