Genetic Mutations of Tim-3 Ligand and Exhausted Tim-3(+) CD8(+) T Cells and Survival in Diffuse Large B Cell Lymphoma

Tim-3 is a promising target for antitumor immunotherapy. A number of clinical trials are evaluating the efficacy of anti-Tim-3 therapies as a single agent or combinations in solid tumors and haematologic malignancies. However, there remains a considerable lack of data on Tim-3 signalling, especially...

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Pubblicato in:J Immunol Res
Autori principali: Zhang, Tingting, Ren, Tianyuan, Song, Zheng, Zhao, Jing, Jiao, Lei, Zhang, Zhenzhen, He, Jin, Liu, Xianming, Qiu, Lihua, Li, Lanfang, Zhou, Shiyong, Meng, Bin, Zhai, Qiongli, Ren, Xiubao, Qian, Zhengzi, Wang, Xianhuo, Zhang, Huilai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7647777/
https://ncbi.nlm.nih.gov/pubmed/33178839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6968595
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