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xCT: A Critical Molecule That Links Cancer Metabolism to Redox Signaling
System x(c)(−) cystine/glutamate antiporter, composed of a light-chain subunit (xCT, SLC7A11) and a heavy-chain subunit (CD98hc, SLC3A2), is mainly responsible for the cellular uptake of cystine in exchange for intracellular glutamate. In recent years, the xCT molecule has been found to play an impo...
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| Publicado no: | Mol Ther |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Gene & Cell Therapy
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7647670/ https://ncbi.nlm.nih.gov/pubmed/32931751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.08.021 |
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