Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans

Rediscovery of cold-activated brown adipose tissue (BAT) in humans has boosted research interest into identifying BAT activators for metabolic benefits. Of particular interest are cytokines capable of fat browning. Irisin, derived from FNDC5, is an exercise-induced myokine that drives brown fat-like...

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Veröffentlicht in:Cell Metab
Hauptverfasser: Lee, Paul, Linderman, Joyce, Smith, Sheila, Brychta, Robert J, Wang, Juan, Idelson, Christopher, Perron, Rachel M, Werner, Charlotte D, Phan, Giao Q, Kammula, Udai S, Kebebew, Electron, Pacak, Karel, Chen, Kong Y, Celi, Francesco S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7647184/
https://ncbi.nlm.nih.gov/pubmed/24506871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.12.017
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