Cathepsin B aggravated doxorubicin-induced myocardial injury via NF-κB signalling

Myocyte apoptosis and oxidative stress key critical roles in the process of doxorubicin (DOX)-induced cardiotoxicity. However, how apoptosis and oxidative stress arise in DOX-induced heart injury remains largely unknown. Cathepsin B (CTSB) is a typical lysosomal cysteine protease that is associated...

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Vydáno v:Mol Med Rep
Hlavní autoři: Liu, Chen, Cai, Zhulan, Hu, Tongtong, Yao, Qi, Zhang, Lijun
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646931/
https://ncbi.nlm.nih.gov/pubmed/33173960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11583
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