Pancreatic Ductal Adenocarcinoma: Characteristics of Tumor Microenvironment and Barriers to Treatment

Pancreatic ductal adenocarcinoma remains a highly aggressive disease, with a 5-year relative survival rate of 10%. Numerous barriers to treatment exist, such as dense desmoplasia, infiltration of immune suppressor cells, inhibitory cytokines, low effector T-cell infiltration, and low tumor mutationa...

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Dades bibliogràfiques
Publicat a:J Adv Pract Oncol
Autors principals: Kane, Sujata, Engelhart, Anne, Guadagno, Jessica, Jones, Aaron, Usoro, Innis, Brutcher, Edith
Format: Artigo
Idioma:Inglês
Publicat: Harborside Press LLC 2020
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646635/
https://ncbi.nlm.nih.gov/pubmed/33575066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6004/jadpro.2020.11.7.4
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