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Pathogenic Heteroplasmic Somatic Mitochondrial DNA Mutation Confers Platinum-Resistance and Recurrence of High-Grade Serous Ovarian Cancer
PURPOSE: Platinum resistance is a primary barrier to improving the survival rate of ovarian cancer. The relationship between mtDNA somatic mutations and response to platinum-based chemotherapy in ovarian cancer has not been well clarified. PATIENTS AND METHODS: Here, we employed the next-generation...
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| Publicat a: | Cancer Manag Res |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Dove
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7646460/ https://ncbi.nlm.nih.gov/pubmed/33173341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S277724 |
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