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Pathogenic Heteroplasmic Somatic Mitochondrial DNA Mutation Confers Platinum-Resistance and Recurrence of High-Grade Serous Ovarian Cancer
PURPOSE: Platinum resistance is a primary barrier to improving the survival rate of ovarian cancer. The relationship between mtDNA somatic mutations and response to platinum-based chemotherapy in ovarian cancer has not been well clarified. PATIENTS AND METHODS: Here, we employed the next-generation...
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| Vydáno v: | Cancer Manag Res |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Dove
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7646460/ https://ncbi.nlm.nih.gov/pubmed/33173341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S277724 |
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