Amide-type local anesthetics may suppress tumor cell proliferation and sensitize Human Hepatocellular Carcinoma Cells to Cisplatin via upregulation of RASSF1A expression and demethylation

Background: It has been reported that local anesthetics are toxic to various types of cells. Furthermore, several local anesthetics have been confirmed to exert demethylation effects and regulate the proliferation of human cancer cells. Our previous findings suggest that lidocaine may exert potentia...

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Publicado en:J Cancer
Autores principales: Chen, Dongtai, Yan, Yan, Xie, Jingdun, Pan, Jiahao, Chen, Yonghua, Li, Qiang, Yuan, Yunfei, Zeng, Weian, Xing, Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2020
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646167/
https://ncbi.nlm.nih.gov/pubmed/33193895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.46630
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