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Clustering of Alzheimer’s and Parkinson’s disease based on genetic burden of shared molecular mechanisms

One of the visions of precision medicine has been to re-define disease taxonomies based on molecular characteristics rather than on phenotypic evidence. However, achieving this goal is highly challenging, specifically in neurology. Our contribution is a machine-learning based joint molecular subtypi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Emon, Mohammad Asif, Heinson, Ashley, Wu, Ping, Domingo-Fernández, Daniel, Sood, Meemansa, Vrooman, Henri, Corvol, Jean-Christophe, Scordis, Phil, Hofmann-Apitius, Martin, Fröhlich, Holger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645798/
https://ncbi.nlm.nih.gov/pubmed/33154531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76200-4
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