Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis

The membrane-anchored matrix metalloprotease MT1-MMP is a potent collagenolytic enzyme with a well-established role in extracellular matrix turnover and cellular invasion into collagen-rich tissues. MT1-MMP is highly expressed in various types of cancer and has been demonstrated to be directly invol...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ingvarsen, Signe Z., Gårdsvoll, Henrik, van Putten, Sander, Nørregaard, Kirstine S., Krigslund, Oliver, Meilstrup, Josephine A., Tran, Collin, Jürgensen, Henrik J., Melander, Maria C., Nielsen, Carsten H., Kjaer, Andreas, Bugge, Thomas H., Engelholm, Lars H., Behrendt, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645741/
https://ncbi.nlm.nih.gov/pubmed/33154487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75995-6
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