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Genome-wide association study of corneal biomechanical properties identifies over 200 loci providing insight into the genetic etiology of ocular diseases

Corneal hysteresis and corneal resistance factor are parameters that reflect the dynamic biomechanical properties of the cornea and have been shown to be biomarkers of corneal disease. In this genome-wide association study of over 100 000 participants, we identified over 200 genetic loci, all but ei...

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Détails bibliographiques
Publié dans:Hum Mol Genet
Auteurs principaux: Simcoe, Mark J, Khawaja, Anthony P, Hysi, Pirro G, Hammond, Christopher J
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645703/
https://ncbi.nlm.nih.gov/pubmed/32716492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa155
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