Nonmuscle myosin IIB regulates Parkin-mediated mitophagy associated with amyotrophic lateral sclerosis-linked TDP-43

C-terminal fragments of Tar DNA-binding protein 43 (TDP-43) have been identified as the major pathological protein in several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). However, how they affect cellular toxicity and neurodegeneration,...

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Udgivet i:Cell Death Dis
Main Authors: Jun, Mi-Hee, Jang, Jae-Woo, Jeon, Pureum, Lee, Soo-Kyung, Lee, Sang-Hoon, Choi, Ha-Eun, Lee, You-Kyung, Choi, Haneul, Park, Sang-Won, Kim, Jeongyeon, Jang, Deok-Jin, Lee, Jin-A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645685/
https://ncbi.nlm.nih.gov/pubmed/33154354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03165-7
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