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The Oscillation Amplitude, Not the Frequency of Cytosolic Calcium, Regulates Apoptosis Induction

Although a rising concentration of cytosolic Ca(2+) has long been recognized as an essential signal for apoptosis, the dynamical mechanisms by which Ca(2+) regulates apoptosis are not clear yet. To address this, we constructed a computational model that integrates known biochemical reactions and can...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Qi, Hong, Li, Xiang, Jin, Zhen, Simmen, Thomas, Shuai, Jianwei
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644924/
https://ncbi.nlm.nih.gov/pubmed/33196017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101671
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