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Assessing the Relationship Between Leukocyte Telomere Length and Cancer Risk/Mortality in UK Biobank and TCGA Datasets With the Genetic Risk Score and Mendelian Randomization Approaches

BACKGROUND: Telomere length is an important indicator of tumor progression and survival for cancer patients. Previous work investigated the associations between genetically predicted telomere length and cancers; however, the types of cancers investigated in those studies were relatively limited or t...

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Publicat a:Front Genet
Autors principals: Gao, Yixin, Wei, Yongyue, Zhou, Xiang, Huang, Shuiping, Zhao, Huashuo, Zeng, Ping
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644901/
https://ncbi.nlm.nih.gov/pubmed/33193711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.583106
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