A circular RNA generated from an intron of the insulin gene controls insulin secretion

Fine-tuning of insulin release from pancreatic β-cells is essential to maintain blood glucose homeostasis. Here, we report that insulin secretion is regulated by a circular RNA containing the lariat sequence of the second intron of the insulin gene. Silencing of this intronic circular RNA in pancrea...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Stoll, Lisa, Rodríguez-Trejo, Adriana, Guay, Claudiane, Brozzi, Flora, Bayazit, Mustafa Bilal, Gattesco, Sonia, Menoud, Véronique, Sobel, Jonathan, Marques, Ana Claudia, Venø, Morten Trillingsgaard, Esguerra, Jonathan Lou S., Barghouth, Mohammad, Suleiman, Mara, Marselli, Lorella, Kjems, Jørgen, Eliasson, Lena, Renström, Erik, Bouzakri, Karim, Pinget, Michel, Marchetti, Piero, Regazzi, Romano
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644714/
https://ncbi.nlm.nih.gov/pubmed/33154349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19381-w
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia