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Chemogenetic selective manipulation of nucleus accumbens medium spiny neurons bidirectionally controls alcohol intake in male and female rats

The nucleus accumbens (NAc), considered the hub of reward circuitry, is comprised of two medium spiny neuron (MSN) subtypes that are classified by their enrichment of dopamine 1 (D1) or 2 (D2) receptors. While reports indicate that alcohol increases excitatory neurotransmission exclusively on NAc D1...

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Vydáno v:Sci Rep
Hlavní autoři: Strong, C. E., Hagarty, D. P., Brea Guerrero, A., Schoepfer, K. J., Cajuste, S. M., Kabbaj, M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644642/
https://ncbi.nlm.nih.gov/pubmed/33154463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76183-2
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