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Hypoxia-inducible factor-2α is crucial for proper brain development

Sufficient tissue oxygenation is required for regular brain function; thus oxygen supply must be tightly regulated to avoid hypoxia and irreversible cell damage. If hypoxia occurs the transcription factor complex hypoxia-inducible factor (HIF) will accumulate and coordinate adaptation of cells to hy...

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Publicat a:Sci Rep
Autors principals: Kleszka, Kira, Leu, Tristan, Quinting, Theresa, Jastrow, Holger, Pechlivanis, Sonali, Fandrey, Joachim, Schreiber, Timm
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644612/
https://ncbi.nlm.nih.gov/pubmed/33154420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75838-4
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