Eculizumab as an emergency treatment for adult patients with severe COVID-19 in the intensive care unit: A proof-of-concept study

BACKGROUND: Complement pathway inhibition may provide benefit for severe acute respiratory illnesses caused by viral infections such as COVID-19. We present results from a nonrandomized proof-of-concept study of complement C5 inhibitor eculizumab for treatment of severe COVID-19. METHODS: All patien...

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Veröffentlicht in:EClinicalMedicine
Hauptverfasser: Annane, Djillali, Heming, Nicholas, Grimaldi-Bensouda, Lamiae, Frémeaux-Bacchi, Véronique, Vigan, Marie, Roux, Anne-Laure, Marchal, Armance, Michelon, Hugues, Rottman, Martin, Moine, Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644240/
https://ncbi.nlm.nih.gov/pubmed/33173853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eclinm.2020.100590
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