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MiR-21 mediates the protection of kaempferol against hypoxia/reoxygenation-induced cardiomyocyte injury via promoting Notch1/PTEN/AKT signaling pathway

Kaempferol, a natural flavonoid compound, possesses potent myocardial protective property in ischemia/reperfusion (I/R), but the underlying mechanism is not well understood. The present study was aimed to explore whether miR-21 contributes to the cardioprotective effect of kaempferol on hypoxia/reox...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Huang, Jinxi, Qi, Zhenhui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644004/
https://ncbi.nlm.nih.gov/pubmed/33151961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241007
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