Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis

Sepsis is the leading cause of death in hospitalized patients and beyond the hospital stay and these long-term sequelae are due in part to unresolved inflammation. Metabolic shift from oxidative phosphorylation to aerobic glycolysis links metabolism to inflammation and such a shift is commonly obser...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bakalov, Veli, Reyes-Uribe, Laura, Deshpande, Rahul, Maloy, Abigail L., Shapiro, Steven D., Angus, Derek C., Chang, Chung-Chou H., Le Moyec, Laurence, Wendell, Stacy Gelhaus, Kaynar, Ata Murat
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643993/
https://ncbi.nlm.nih.gov/pubmed/33151963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241122
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