Enhanced Enterovirus D68 Replication in Neuroblastoma Cells Is Associated with a Cell Culture-Adaptive Amino Acid Substitution in VP1

Since its emergence in the United States in 2014, enterovirus D68 (EV-D68) has been and is associated with severe respiratory diseases and acute flaccid myelitis. Even though EV-D68 has been shown to replicate in different neuronal cells in vitro, it is currently poorly understood which viral factor...

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Udgivet i:mSphere
Main Authors: Sooksawasdi Na Ayudhya, Syriam, Meijer, Adam, Bauer, Lisa, Oude Munnink, Bas, Embregts, Carmen, Leijten, Lonneke, Siegers, Jurre Y., Laksono, Brigitta M., van Kuppeveld, Frank, Kuiken, Thijs, GeurtsvanKessel, Corine, van Riel, Debby
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643833/
https://ncbi.nlm.nih.gov/pubmed/33148825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00941-20
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