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Colesevelam enhances the beneficial effects of brown fat activation on hyperlipidaemia and atherosclerosis development

AIMS: Brown fat activation accelerates the uptake of cholesterol-enriched remnants by the liver and thereby lowers plasma cholesterol, consequently protecting against atherosclerosis development. Hepatic cholesterol is then converted into bile acids (BAs) that are secreted into the intestine and lar...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Zhou, Enchen, Hoeke, Geerte, Li, Zhuang, Eibergen, Arthur C, Schonk, Amber W, Koehorst, Martijn, Boverhof, Renze, Havinga, Rick, Kuipers, Folkert, Coskun, Tamer, Boon, Mariëtte R, Groen, Albert K, Rensen, Patrick C N, Berbée, Jimmy F P, Wang, Yanan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643538/
https://ncbi.nlm.nih.gov/pubmed/31589318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvz253
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