Low-density lipoprotein receptor (LDLR) regulates NLRP3-mediated neuronal pyroptosis following cerebral ischemia/reperfusion injury

BACKGROUND: Inflammatory response has been recognized as a pivotal pathophysiological process during cerebral ischemic stroke. NLRP3 inflammasome, involved in the regulation of inflammatory cascade, can simultaneously lead to GSDMD-executed pyroptosis in cerebral ischemia. Low-density lipoprotein re...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Sun, Rui, Peng, Mengna, Xu, Pengfei, Huang, Feihong, Xie, Yi, Li, Juanji, Hong, Ye, Guo, Hongquan, Liu, Qian, Zhu, Wusheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643474/
https://ncbi.nlm.nih.gov/pubmed/33153475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01988-x
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