TM4SF1 promotes EMT and cancer stemness via the Wnt/β-catenin/SOX2 pathway in colorectal cancer

BACKGROUND: Transmembrane 4 L six family member 1 (TM4SF1) is upregulated in several epithelial cancers and is closely associated with poor prognosis. However, the role of TM4SF1 and its potential mechanism in colorectal cancer (CRC) remain elusive. METHODS: We investigated the expression of TM4SF1...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Tang, Qiang, Chen, Jinhuang, Di, Ziyang, Yuan, Wenzheng, Zhou, Zili, Liu, Zhengyi, Han, Shengbo, Liu, Yanwei, Ying, Guoguang, Shu, Xiaogang, Di, Maojun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643364/
https://ncbi.nlm.nih.gov/pubmed/33153498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01690-z
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