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Rapid and Efficient Microwave‐Assisted Friedländer Quinoline Synthesis

A microwave‐based methodology facilitates reaction of 2‐aminophenylketones with cyclic ketones to form a quinoline scaffold. Syntheses of amido‐ and amino‐linked 17β‐hydroxysteroid dehydrogenase type 3 inhibitors with a benzophenone‐linked motif were pursued using 2‐aminobenzophenone as building blo...

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Detalhes bibliográficos
Publicado no:ChemistryOpen
Main Authors: Bailey, Helen V., Mahon, Mary F., Vicker, Nigel, Potter, Barry V. L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643340/
https://ncbi.nlm.nih.gov/pubmed/33194530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.202000247
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