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Biological interpretation of deep neural network for phenotype prediction based on gene expression

BACKGROUND: The use of predictive gene signatures to assist clinical decision is becoming more and more important. Deep learning has a huge potential in the prediction of phenotype from gene expression profiles. However, neural networks are viewed as black boxes, where accurate predictions are provi...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Hanczar, Blaise, Zehraoui, Farida, Issa, Tina, Arles, Mathieu
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643315/
https://ncbi.nlm.nih.gov/pubmed/33148191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03836-4
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