Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer’s disease features in cortical neurons

BACKGROUND: After decades of research recognizing it as a complex multifactorial disorder, sporadic Alzheimer’s disease (sAD) still has no known etiology. Adding to the myriad of different pathways involved, bacterial neurotoxins are assuming greater importance in the etiology and/or progression of...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Silva, Diana F., Candeias, Emanuel, Esteves, A. Raquel, Magalhães, João D., Ferreira, I. Luísa, Nunes-Costa, Daniela, Rego, A. Cristina, Empadinhas, Nuno, Cardoso, Sandra M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643281/
https://ncbi.nlm.nih.gov/pubmed/33153477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-02004-y
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