Mitochondrial Fission Factor (MFF) Inhibits Mitochondrial Metabolism and Reduces Breast Cancer Stem Cell (CSC) Activity

Elevated mitochondrial biogenesis and metabolism represent key features of breast cancer stem cells (CSCs), whose propagation is conducive to disease onset and progression. Therefore, interfering with mitochondria biology and function may be regarded as a useful approach to eradicate CSCs. Here, we...

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Vydáno v:Front Oncol
Hlavní autoři: Sánchez-Alvarez, Rosa, De Francesco, Ernestina Marianna, Fiorillo, Marco, Sotgia, Federica, Lisanti, Michael P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642822/
https://ncbi.nlm.nih.gov/pubmed/33194575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01776
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