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Cortisone and cortisol break hydrogen-bonding rules to make a drug–prodrug solid solution

Multidrug products enable more effective therapies and simpler administration regimens, provided that a stable formulation is prepared, with the desired composition. In this view, solid solutions have the advantage of combining the stability of a single crystalline phase with the potential of stoich...

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Библиографические подробности
Опубликовано в: :IUCrJ
Главные авторы: Verma, Vivek, Bordignon, Simone, Chierotti, Michele R., Lestari, Monica, Lyons, Kieran, Padrela, Luis, Ryan, Kevin M., Lusi, Matteo
Формат: Artigo
Язык:Inglês
Опубликовано: International Union of Crystallography 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642785/
https://ncbi.nlm.nih.gov/pubmed/33209323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252520013263
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