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Extracellular vesicles report on the MET status of their cells of origin regardless of the method used for their isolation

MET pathway is an important actionable target across many solid tumour types and several MET inhibitors have been developed. Extracellular vesicles (EVs) are proposed to be mini-maps of their cells of origin. However, the potential of EVs to report on the MET status of their cells of origin is unkno...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Useckaite, Zivile, Mukhopadhya, Anindya, Moran, Barry, O’Driscoll, Lorraine
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642384/
https://ncbi.nlm.nih.gov/pubmed/33149187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75817-9
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