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Native Cell Environment Constrains Loop Structure in the Escherichia coli Cobalamin Transporter BtuB

The extracellular loops of bacterial outer membrane (OM) transporters are thought to sample a range of conformations in the apo state but to undergo a gating motion and assume a more defined conformation upon the binding of substrate. Here, we use pulse electron paramagnetic resonance to examine the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Nyenhuis, David A., Nilaweera, Thushani D., Cafiso, David S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642247/
https://ncbi.nlm.nih.gov/pubmed/32946767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.08.034
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