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Interplay between V-ATPase G1 and small EV-miRNAs modulates ERK1/2 activation in GBM stem cells and non-neoplastic milieu

The ATP6V1G1 subunit (V1G1) of the vacuolar proton ATPase (V-ATPase) pump is crucial for glioma stem cells (GSC) maintenance and in vivo tumorigenicity. Moreover, V-ATPase reprograms the tumor microenvironment through acidification and release of extracellular vesicles (EVs). Therefore, we investiga...

詳細記述

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書誌詳細
出版年:Mol Cancer Res
主要な著者: Bertolini, Irene, Storaci, Alessandra Maria, Terrasi, Andrea, Di Cristofori, Andrea, Locatelli, Marco, Caroli, Manuela, Ferrero, Stefano, Altieri, Dario C., Vaira, Valentina
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642188/
https://ncbi.nlm.nih.gov/pubmed/32753475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0078
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