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Mining and Statistical Modeling of Natural and Variant Class IIa Bacteriocins Elucidate Activity and Selectivity Profiles across Species

Class IIa bacteriocin antimicrobial peptides (AMPs) are a compelling alternative to current antimicrobials because of potential specific activity toward antibiotic-resistant bacteria, including vancomycin-resistant enterococci. Engineering of these molecules would be enhanced by a better understandi...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Tresnak, Daniel T., Hackel, Benjamin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642072/
https://ncbi.nlm.nih.gov/pubmed/32917749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01646-20
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