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Neurobiologic Rationale for Treatment of Apathy in Alzheimer’s Disease With Methylphenidate

The public health burden of Alzheimer’s disease (AD) is related not only to cognitive symptoms, but also to neuropsychiatric symptoms, including apathy. Apathy is defined as a quantitative reduction of goal-directed activity in comparison to a previous level of functioning and affects 30%–70% of per...

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Detalhes bibliográficos
Publicado no:Am J Geriatr Psychiatry
Main Authors: van Dyck, Christopher H., Arnsten, Amy F.T., Padala, Prasad R., Brawman-Mintzer, Olga, Lerner, Alan J., Porsteinsson, Anton P., Scherer, Roberta W., Levey, Allan I., Herrmann, Nathan, Jamil, Nimra, Mintzer, Jacobo E., Lanctôt, Krista L., Rosenberg, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641967/
https://ncbi.nlm.nih.gov/pubmed/32461027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jagp.2020.04.026
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