hPMSCs protects against d-galactose-induced oxidative damage of CD4(+) T cells through activating Akt-mediated Nrf2 antioxidant signaling

BACKGROUND: Mesenchymal stem cells (MSCs) were considered a regenerative therapeutic approach in both acute and chronic diseases. However, whether MSCs regulate the antioxidant metabolism of CD4(+) T cells and weaken immunosenescence remains unclear. Here, we reported the protective effects of hPMSC...

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Publicat a:Stem Cell Res Ther
Autors principals: Xiong, Yanlian, Wang, Yueming, Zhang, Jiashen, Zhao, Nannan, Zhang, Hengchao, Zhang, Aiping, Zhao, Dongmei, Yu, Zhenhai, Yin, Yancun, Song, Lele, Xiong, Yanlei, Luan, Xiying
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641865/
https://ncbi.nlm.nih.gov/pubmed/33148324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01993-0
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