Mechanism of efficient double-strand break repair by a long non-coding RNA

Mechanistic studies in DNA repair have focused on roles of multi-protein DNA complexes, so how long non-coding RNAs (lncRNAs) regulate DNA repair is less well understood. Yet, lncRNA LINP1 is over-expressed in multiple cancers and confers resistance to ionizing radiation and chemotherapeutic drugs....

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Thapar, Roopa, Wang, Jing L, Hammel, Michal, Ye, Ruiqiong, Liang, Ke, Sun, Chengcao, Hnizda, Ales, Liang, Shikang, Maw, Su S, Lee, Linda, Villarreal, Heather, Forrester, Isaac, Fang, Shujuan, Tsai, Miaw-Sheue, Blundell, Tom L, Davis, Anthony J, Lin, Chunru, Lees-Miller, Susan P, Strick, Terence R, Tainer, John A
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Genome Integrity, Repair and Replication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641761/
https://ncbi.nlm.nih.gov/pubmed/33045735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa784
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