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Oxidative stress and glutamate excretion in alcoholic steatosis: Metabolic synapse between hepatocyte and stellate cell

Chronic alcohol consumption induces the development of alcoholic steatosis in the liver, which is one of the most widespread liver diseases worldwide. During general alcohol metabolism, hepatocytes generate mitochondria- and cytochrome P450 2E1 (CYP2E1)-mediated reactive oxygen species (ROS) whose a...

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Publicat a:Clin Mol Hepatol
Autors principals: Kim, Hee-Hoon, Choi, Sung Eun, Jeong, Won-Il
Format: Artigo
Idioma:Inglês
Publicat: The Korean Association for the Study of the Liver 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641576/
https://ncbi.nlm.nih.gov/pubmed/33053940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3350/cmh.2020.0152
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