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The chromatin landscape at the HIV-1 provirus integration site determines viral expression
HIV-1 persists lifelong in memory cells of the immune system as latent provirus that rebounds upon treatment interruption. Therefore, the latent reservoir is the main target for an HIV cure. Here, we studied the direct link between integration site and transcription using LEDGINs and Barcoded HIV-en...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7641320/ https://ncbi.nlm.nih.gov/pubmed/32597987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa536 |
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