Establishment and characterisation of testicular cancer patient-derived xenograft models for preclinical evaluation of novel therapeutic strategies

Testicular cancer (TC) is the most common solid tumour in young men. While cisplatin-based chemotherapy is highly effective in TC patients, chemoresistance still accounts for 10% of disease-related deaths. Pre-clinical models that faithfully reflect patient tumours are needed to assist in target dis...

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Vydáno v:Sci Rep
Hlavní autoři: de Vries, Gerda, Rosas-Plaza, Ximena, Meersma, Gert Jan, Leeuwenburgh, Vincent C., Kok, Klaas, Suurmeijer, Albert J. H., van Vugt, Marcel A. T. M., Gietema, Jourik A., de Jong, Steven
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641131/
https://ncbi.nlm.nih.gov/pubmed/33144587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75518-3
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