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The transition from primary colorectal cancer to isolated peritoneal malignancy is associated with an increased tumour mutational burden

Colorectal Peritoneal metastases (CPM) develop in 15% of colorectal cancers. Cytoreductive surgery and heated intraperitoneal chemotherapy (CRS & HIPEC) is the current standard of care in selected patients with limited resectable CPM. Despite selection using known prognostic factors survival is...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hallam, Sally, Stockton, Joanne, Bryer, Claire, Whalley, Celina, Pestinger, Valerie, Youssef, Haney, Beggs, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641117/
https://ncbi.nlm.nih.gov/pubmed/33144643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75844-6
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