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A Combination of Tri-Leucine and Angiopep-2 Drives a Polyanionic Polymalic Acid Nanodrug Platform Across the Blood–Brain Barrier

One of the major problems facing the treatment of neurological disorders is the poor delivery of therapeutic agents into the brain. Our goal is to develop a multifunctional and biodegradable nanodrug delivery system that crosses the blood—brain barrier (BBB) to access brain tissues affected by neuro...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Israel, Liron L., Braubach, Oliver, Galstyan, Anna, Chiechi, Antonella, Shatalova, Ekaterina S., Grodzinski, Zachary, Ding, Hui, Black, Keith L., Ljubimova, Julia Y., Holler, Eggehard
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641102/
https://ncbi.nlm.nih.gov/pubmed/30633492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b06437
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