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Acute IL-4 Governs Pathogenic T Cell Responses during Leishmania major Infection

Leishmania spp. infection is a global health problem affecting more than 2 million people every year with 300 million at risk worldwide. It is well established that a dominant Th1 response (IFN-γ, a hallmark Th1 cytokine) provides resistance, whereas a dominant Th2 response (IL-4, a hallmark Th2 cyt...

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Bibliografische gegevens
Gepubliceerd in:Immunohorizons
Hoofdauteurs: Poudel, Barun, Yorek, Matthew S., Mazgaeen, Lalita, Brown, Scott A., Kanneganti, Thirumala-Devi, Gurung, Prajwal
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7640617/
https://ncbi.nlm.nih.gov/pubmed/32948646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.2000076
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