RECIST and iRECIST criteria for the evaluation of nivolumab plus ipilimumab in patients with microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer: the GERCOR NIPICOL phase II study

BACKGROUND: Immune checkpoint inhibitors (ICIs) are highly effective in patients with microsatellite instability/mismatch repair-deficient (MSI/dMMR) metastatic colorectal cancer (mCRC). Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 criteria may underestimate response to ICIs due to the...

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Pubblicato in:J Immunother Cancer
Autori principali: Cohen, Romain, Bennouna, Jaafar, Meurisse, Aurélia, Tournigand, Christophe, De La Fouchardière, Christelle, Tougeron, David, Borg, Christophe, Mazard, Thibault, Chibaudel, Benoist, Garcia-Larnicol, Marie-Line, Svrcek, Magali, Vernerey, Dewi, Menu, Yves, André, Thierry
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2020
Soggetti:
Clinical/Translational Cancer Immunotherapy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7640587/
https://ncbi.nlm.nih.gov/pubmed/33148693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001499
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