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Clathrin- and dynamin-dependent endocytosis limits canonical NF-κB signaling triggered by lymphotoxin β receptor

BACKGROUND: Lymphotoxin β receptor (LTβR) is a member of tumor necrosis factor receptor (TNFR) superfamily which regulates the immune response. At the cellular level, upon ligand binding, the receptor activates the pro-inflammatory NF-κB and AP-1 pathways. Yet, the intracellular distribution of LTβR...

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Publicado en:Cell Commun Signal
Autores principales: Maksymowicz, Małgorzata, Miączyńska, Marta, Banach-Orłowska, Magdalena
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7640449/
https://ncbi.nlm.nih.gov/pubmed/33148272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00664-0
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