Predisposition footprints in the somatic genome of Wilms tumours

Ten percent of children with cancer harbour a mutation in a predisposition gene. In children with the kidney cancer, Wilms tumour, the prevalence is as high as 30%. Certain predispositions are associated with defined histological and clinical features, suggesting differences in tumourigenesis. To in...

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Udgivet i:Cancer Discov
Main Authors: Treger, Taryn D., Wegert, Jenny, Wenger, Anna, Coorens, Tim H. H., Al-Saadi, Reem, Kemps, Paul G., Kennedy, Jonathan, Parks, Conor, Anderson, Nathaniel D., Hodder, Angus, Letunovska, Aleksandra, Jung, Hyunchul, Ogbonnah, Toochi, Trinh, Mi K., Lee-Six, Henry, Morcrette, Guillaume, van den Heuvel-Eibrink, Marry M, Drost, Jarno, van Boxtel, Ruben, Bertrums, Eline J.M., Goemans, Bianca F., Antoniou, Evangelia, Reinhardt, Dirk, Streitenberger, Heike, Ziegler, Barbara, Bartram, Jack, Ciaran Hutchinson, J., Vujanic, Gordan M., Vokuhl, Christian, Chowdhury, Tanzina, Furtwängler, Rhoikos, Graf, Norbert, Pritchard-Jones, Kathy, Gessler, Manfred, Behjati, Sam
Format: Artigo
Sprog:Inglês
Udgivet: 2024
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617291/
https://ncbi.nlm.nih.gov/pubmed/39665570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-24-0878
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